Blog 5 Things You Didn’t Know About Depression and Mood Swings 👩 Women are twice as likely as men to develop depression. 😷 Even a light depression can impair the immune system. 🌿 23 clinical studies found that St John’s Wort was equally effective as pharmaceutical therapy for moderate depression. 🌎 Depression affects people of all ages, races and nationalities according to the World Health Organization. 🚑 One out of eight people will kill themselves during a major depression.